Analysis of Symptoms, Approaches to Therapy and Outcomes of Synthetic Cathinone-Induced Delirium: Systematic Review

INTRODUCTION: One of the important disorders that can be induced by using synthetic cathinones (SC) is delirium, differentiated from other psychotic complications in ICD-11. The article presents a systematic review literature with aim to describe symptoms, effectiveness empirical approaches therapy and probable outcomes delirium SC. analysis scientific publications eLibrary, CNKI, PubMed, Scopus databases was performed search keywords. In accordance recommendations PRISMA, 23 articles were selected. CONCLUSION: Most found about MDPV-induced delirium. No exact dose range SC cause specified. Delirium more often described after prolonged use (for 1 month), rare cases single use. most develops within few hours intake associated intoxication, rather than withdrawal syndrome. clinical picture studied conditions, besides triad main symptoms includes psychomotor excitement pronounced sympathicotonia, vast majority (acute sensory paranoid syndrome, true visual hallucinations, insomnia, aggressiveness expressed form hetero- or autoaggression) are also present. Of highest benzodiazepines antipsychotics detoxification general resuscitation measures. resulted complete recovery, deaths serotonin suicides, accidents against background acute somatic diseases underlying sympathicotonia.